Nonsense-mediated mRNA decay (NMD) controls eukaryotic mRNA quality, inducing the degradation of faulty transcripts.Key players in the NMD pathway were originally identified, through genetics, in Caenorhabditis elegans as smg (suppressor with Dinnerware Sets morphological effect on genitalia) genes.Using forward genetics and fluorescence-based NMD

Multiple myeloma (MM) is a hematological malignancy characterized by the presence of clonal plasma cells in the bone marrow niche.Despite significant therapeutic advances, MM remains incurable for the majority of patients.Targeted radionuclide therapy (TRNT) has emerged as a promising treatment option to eradicate residual Basketball cancer cells.I